Cycloaliphatic ketoamines

Details Cycloaliphatic ketoamines Cycloaliphatic ketoamines

A - Human Necessities

61

K

260/603.6, 260/5

A61K 31/13 (2006.01) A61K 31/135 (2006.01) A61K 31/43 (2006.01)

Patent

CA 1123826

The present invention proviaes a compound having the formula Image I wherein X represents the group >CO or >CH(OH), R2 represents hydrogen or a C1 to C6 alkyl group, R3 represents hydrogen or a hydroxy group and R1 represents the adamantyl radical or a saturated or mono-unsaturated C3 to C16 -cycloalkyl radical which cycloalkyl radical may be substituted by a C1 to C4 - alkyl group or a halogen atom, or a pharmaceutically acceptable salt thereof. Such compounds are pharmacodynamically active and cause, for example, a decrease of blood pressure and an improve- ment of cerebral or peripheral blood flow. Moreover, they have an antiphlogistic effect and are distinguished by good resorption.

327735

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