Cycloaliphatic pharmaceutical compounds

Details Cycloaliphatic pharmaceutical compounds Cycloaliphatic pharmaceutical compounds

C - Chemistry, Metallurgy

07

C

260/581, 260/646

C07C 35/00 (2006.01) C07C 49/487 (2006.01) C07C 49/517 (2006.01)

Patent

CA 1246604

ABSTRACT OF THE DISCLOSURE Novel pharmaceutical compounds, useful in anti-? genic compositions, have the formulae: (I) (II) Image In these formulae: B and B' are both H or together form a single bond; M1 and M2 are H, Cl, Br or I Q is CO, CH-OR, or CR-OH; each X is independently H or A; Y and Y' are independently H, halo. or A; A is -CRR-(CR1R2)nR3 n is an integer of from one to eight; R is H or lower alkyl; each R1 and R2 is independently R, OR, COOH, CHO, or CR1R2 together form the group CO; R3 is H, COOR, OR, CHR-OR or COR; c is an integer from zero to four; and d is three or four; and p is zero or one provided that at least one A group is present and each A group contains at least one of COOR, CHO, CO, OR and COR, and not more than one of COOH, CO or COR, and wherein up to two ethylenic bonds may be present in the ring shown above. Pharmaceutically-acceptable salts of these compounds also are provided.

444901

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