Cycloalkyl amino-hydantoin compounds and use thereof for...

Details Cycloalkyl amino-hydantoin compounds and use thereof for... Cycloalkyl amino-hydantoin compounds and use thereof for...

C - Chemistry, Metallurgy

07

D

C07D 233/88 (2006.01) A61K 31/4168 (2006.01) A61P 25/28 (2006.01) C07D 233/54 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 409/06 (2006.01)

Patent

CA 2616510

The present invention provides a 2-amino-5-cycloalkyl-hydantoin compound of formula (I) The present invention also provides methods and compositions for the inhibition of ~-secretase (BACE) and the treatment of ~-amyloid deposits and neurofibrillary tangles.

L'invention concerne un composé de 2-amino-5-cycloalkyl-hydantoin représenté par la formule (I). L'invention concerne également des méthodes et des compositions permettant d'inhiber la ß-secrétase (BACE) et de traiter les dépôts ß-amyloïdes et les enchevêtrements neurofibrillaires.

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