Cycloalkyl - substituted 4-pyridyl derivatives and process...

Details Cycloalkyl - substituted 4-pyridyl derivatives and process... Cycloalkyl - substituted 4-pyridyl derivatives and process...

C - Chemistry, Metallurgy

07

D

167/228, 260/296

C07D 213/24 (2006.01) A61K 31/44 (2006.01) C07D 213/16 (2006.01) C07D 213/18 (2006.01) C07D 213/30 (2006.01) C07D 213/38 (2006.01) C07D 213/40 (2006.01) C07D 213/50 (2006.01) C07D 213/55 (2006.01) C07D 213/56 (2006.01)

Patent

CA 1294624

A B S T R A C T The invention relates to cycloalkyl-substituted 4-pyridyl deri- vatives of formula (I) Image (1) wherein R is C1-C4 alkyl; each of R1 and R2 is, independently, hydrogen or C1-C4 alkyl; n is an integer of 1 to 5; and either (a) A is ?C=O and B is -O-, -NH- or -CH2-; or (b) A ls -CH2- and B is -O-, -NH-, -CH2- or ?C=O; or (c) A is -O- and B is ?C=O or -CH2-; or (d) A is -NH- and B is ?C=O or -CH2-, and their pharmaceutically acceptable salts. The compounds of the invention show aromatase inhibiting activity and can be useful, e.g., in treating hormone-dependent tumors and prostatic hyperplasia.

542253

Affiliated with

Also associated with

Rating

Cycloalkyl - substituted 4-pyridyl derivatives and process... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cycloalkyl - substituted 4-pyridyl derivatives and process..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cycloalkyl - substituted 4-pyridyl derivatives and process... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1222348