Cycloalkylamine derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 211/35 (2006.01) A61K 31/135 (2006.01) A61K 31/4015 (2006.01) A61K 31/4418 (2006.01) C07D 207/26 (2006.01) C07D 207/32 (2006.01)

Patent

CA 2590985

The present invention relates to compounds of formula (I) wherein Rl is as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly non- insulin dependent diabetes mellitus, and impaired glucose tolerance.

La présente invention concerne des composés de formule (I) dans lesquels Rl est tel que défini dans la description et les revendications, et des sels pharmaceutiquement acceptables de ceux-ci. Les composés sont utiles pour le traitement et/ou la prophylaxie de maladies qui sont associées à la DDP-IV, notamment le diabète, particulièrement le diabète sucré non insulinodépendant, et une mauvaise tolérance au glucose.

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