C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 217/24 (2006.01) A61K 31/472 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2673922
The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
L'invention concerne des dérivés d'isoquinoline et d'isoquinolinone 6-substitués représentés par la formule (I), utilisés dans le traitement et/ou la prévention de maladies associées à la Rho-kinase et/ou à la phosphorylation médiée par la Rho-kinase de la phosphatase de la chaîne légère de la myosine, et des compositions contenant lesdits composés.
Biscarrat Sandrine
Duclot Olivier
Goerlitzer Jochen
Jeannot Frederic
Loehn Matthias
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis
LandOfFree
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