C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/04 (2006.01) A61K 31/4245 (2006.01) A61K 31/4439 (2006.01) A61K 31/506 (2006.01) A61P 9/00 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01) C07D 213/38 (2006.01) C07D 271/06 (2006.01) C07D 271/10 (2006.01) C07D 401/04 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2651629
The invention relates to compounds of formula (I) and to pharmaceutically acceptable salts, prodrugs, solvates or hydrates thereof; wherein B, D, E, R1, R2, R3, R4, R5, R8, m, n, p, q, r, s, t and u are as defined herein. This invention also relates to a method of using such compounds in the treatment of hyperproliferative diseases and autoimmune diseases in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
L'invention concerne des composés ayant la formule (I) et leurs sels pharmaceutiquement acceptables, leurs promédicaments, leurs solvates et leurs hydrates; B, D, E, R1, R2, R3, R4, R5, R8, m, n, p, q, r, s, t et u sont définis dans l'invention. L'invention concerne également un procédé pour utiliser ces composés dans le traitement de maladies hyperprolifératives et de maladies auto-immunes chez les mammifères (notamment chez l'humain) et des compositions pharmaceutiques contenant ces composés.
Bhattacharya Samit Kumar
Brown Matthew Frank
Dorff Peter Hans
Lagreca Susan
Maguire Robert John
Pfizer Products Inc.
Smart & Biggar
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