C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/065 (2006.01)
Patent
CA 2636761
It is intended to provide a cycloalkylcarbonylamino acid derivative which is a raw material intermediate for a novel cycloalkanecarboxamide derivative having a selective cathepsin K inhibitory action and a process for producing the same. The cycloalkylcarbonylamino acid derivative represented by the general formula (I) or a pharmaceutically acceptable salt thereof. (I) [In the formula, R1 and R2 represent an alkyl group, an alkenyl group, an alkynyl group, an aromatic hydrocarbon group, a heterocyclic group or the like, and the ring A represents a cyclic alkylidene group having 5, 6 or 7 carbon atoms.]
L'invention concerne l'obtention d'un dérivé d'acide cycloalkylcarbonylamino qui est un intermédiaire de matière première pour un nouveau dérivé de cycloalcanecarboxamide possédant une action inhibitrice sélective sur la cathepsine K, ainsi que son procédé de production. L'invention concerne ce dérivé d'acide cycloalkylcarbonylamino, représenté par la formule générale (I), ou un de ses sels de qualité pharmaceutique. [Dans la formule générale (I), R1 et R2 désignent un groupe alkyle, un groupe alcényle, un groupe alcynyle, un groupe hydrocarbure aromatique, un groupe hétérocyclique ou analogue et le cycle A désigne un groupe alkylidène cyclique comportant 5, 6 ou 7 atomes de carbone.]
Kobayashi Nobuo
Koji Tsuneo
Kunii Hisatomo
Seikagaku Corporation
Sim & Mcburney
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