Cycloalkylfused indole, benzothiophene, benzofuran and...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 493/04 (2006.01) A61K 31/381 (2006.01) A61K 31/407 (2006.01) A61K 31/4741 (2006.01) A61P 25/24 (2006.01) C07D 209/88 (2006.01) C07D 233/76 (2006.01)

Patent

CA 2597616

The present invention provides cycloalkylfused indole, benzothiophene, benzofuran, and indene derivatives, and methods for using them to, for example, treat, prevent and/or ameliorate central nervous system diseases by antagonizing 5-HT1A receptors and modulating serotonin levels.

L'invention concerne des dérivés d'indole, benzothiophène, benzofurane et indène à fusion cycloalkyle, ainsi que leurs méthodes d'utilisation afin, par exemple, de traiter, prévenir et/ou améliorer des maladies du système nerveux central, ce qui consiste à exercer une action antagoniste sur les récepteurs de 5-HT1A et à moduler les niveaux de sérotonine.

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