Cycloamine ccr5 receptor antagonists

Details Cycloamine ccr5 receptor antagonists Cycloamine ccr5 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/404 (2006.01)

Patent

CA 2393757

Remedies or prophylactics for diseases in association with CCR5 such as AIDS, rheumatoid arthritis or nephritis comprising a cyclic amine compound represented by the following formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, as an active ingredient. (see formula I)

L'invention porte sur des agents thérapeutiques ou préventifs de maladies liées au CCR5 telles que le SIDA, la polyarthrite rhumatoïde et les néphrites, contenant comme principe actif des dérivés de la cycloamine de formule générale (I) ou leurs adduits pharmacocompatibles avec des acides ou leurs adduits pharmacocompatibles avec du C1-6 alkyle.

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