Cyclodextrin liposomes encapsulating pharmacologic compounds...

Details Cyclodextrin liposomes encapsulating pharmacologic compounds... Cyclodextrin liposomes encapsulating pharmacologic compounds...

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2161225

Liposomes containing cyclodextrin in the encapsulated aqueous phase are useful for encapsulation of biologically active substances, especially those which are hydrophilic. The encapsulated cyclodextrin facilitates a slow, controlled please of pharmacologic compounds from the liposomes. The novel methods of the present invention allow the treatment of a variety of pathophysiological states by administering the cyclodextrin-containing liposomes encapsulating the pharmacologic compounds. The present invention also provides a novel method of extending the half lift of a pharmacologic compound in an animal.

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