Cycloheptene derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/202.5

C07D 295/02 (2006.01) C07D 295/03 (2006.01)

Patent

CA 1157853

RAN 4016/16 Abstract The novel 1-[2-(4,5,10,11-tetrahydro-1H-dibenzo- [a,d]cyclohepten-5-yl)ethyl]pyrrolidine of the formula Image I and its pharmaceutically acceptable acid addition salts have valuable histamine-H1 antagonistic properties and are suitable for the control or prevention of allergic reactions such as urticaria, hay fever, anaphylaxis and over-sensitivity to medicaments. These compounds can be manufactured according to various processes starting from partly novel starting materials and can be used in galenical administration forms.

393170

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