Cyclohexane tetrols and derivatives thereof

Details Cyclohexane tetrols and derivatives thereof Cyclohexane tetrols and derivatives thereof

C - Chemistry, Metallurgy

07

C

260/292, 260/325

C07C 13/24 (2006.01) C07C 33/34 (2006.01) C07D 207/06 (2006.01) C07D 211/14 (2006.01) C07D 211/18 (2006.01) C07D 211/22 (2006.01) C07D 213/80 (2006.01) C07D 295/04 (2006.01) C07D 295/096 (2006.01)

Patent

CA 1050025

Abstract This invention relates to cyclohexane tetrol derivatives of the formula Image wherein Y is a radical of the formula Image or of the formula Image wherein (CH2) is a straight or branched chain alkyl radical, n is 1-6, m is O or 1 and R5 and R6 are the same or different and may be hydrogen, alkyl, arylalkyl or dialkylamino-alkyl or R5 and R6 together with the nitrogen to which they are attached are pyrrolidino, piperidino or N'- alkyl piperazino; R1, R2, R3 or R4 are the same or different and are alkanoyl, haloalkanoyl, alkoxycarbonyl of the formula Image wherein R is an alkyl radical; aminoalkanoyl of the formula Image wherein R5 and R6 are as previously defined and p is 0-3, 2-, 3-, or 4-pyridylcarbonyl, alkenoyl or aroyl; R7 and R8 are the same or different and may be hydrogen or alkyl, or R7 and R8 taken together with the carbon atoms bearing sub- stituents OR1 and OR3 form a cycloalkyl ring, R9 is H, or a straight or branched chain alkyl radical of 1-6 carbon atoms and physiologically acceptable acid addition salts thereof, intermediates therefor and processes for these compounds which are useful in the treatment of hypertension in mammalian species, as surface active agents, as in vitro antibacterial compounds and as water softeners.

205218

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