Cyclohexanecarboxylic acid compound

Details Cyclohexanecarboxylic acid compound Cyclohexanecarboxylic acid compound

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/404 (2006.01) A61P 1/00 (2006.01) A61P 3/10 (2006.01) A61P 11/06 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 25/00 (2006.01) A61P 27/16 (2006.01) A61P 29/00 (2006.01) A61P 35/04 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2528586

A VLA-4 inhibitory drug which has high solubility in water and satisfactory long-term stability. It is sodium trans-4-[1-[2,5-dichloro-4-[(1-methyl~1H-3- indolylcarbonyl)amino]phenylacetyl]-(4S)-methoxy-(2S)- pyrrolidinylmethoxy]cyclohexanecarboxylate pentahydrate.

L'invention concerne un médicament inhibiteur de VLA-4 présentant une solubilité dans l'eau élevée et une stabilité à long terme satisfaisante. Ce médicament est du sodium trans-4-[1-[2,5-dichloro-4-[(1-méthyl-1H-3-indolylcarbonyl)amino]phénylacétyl]-(4S)-méthoxy-(2S)-pyrrolidinylméthoxy]cyclohexanecarboxylate pentahydrate.

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