C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 35/17 (2006.01) A61K 31/045 (2006.01) C07F 7/18 (2006.01)
Patent
CA 2288629
The compound, (E)-(1R,3R)-5-[(R)-11-hydroxy-7,11-dimethyl-dodec-2-enylidene]- cyclohexane-1,3-diol of formula (I) is useful in the treatment or prevention of hyperproliferative skin diseases, particularly psoriasis, basal cell carcinomas, disorders of keratinization and keratosis; or for reversing the conditions associated with photodamage.
L'invention concerne le composé (E)-(1R, 3R)-5-[(R)-11-hydroxy-7,11-diméthyl-dodec-2-énylidène]-cyclohexane-1,3-diol représenté par la formule I et convenant particulièrement au traitement ou à la prévention de maladies hyperprolifératives de la peau, particulièrement le psoriasis, le carcinome basocellulaire, les troubles de la kératinisation ou la kératose ou pour inverser le cours de maladies liées aux effets nocifs du soleil.
Bauer Franz
Courtney Lawrence F.
Basilea Pharmaceutica Ag
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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