C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2733153
The present invention relates to cyclohexylol-substituted heterocyclics of the general formula (I), stereoisomers thereof, mixtures thereof and salts thereof, in particular physiologically compatible salts thereof containing inorganic or organic acids having valuable pharmacological properties, in particular an inhibiting effect on the signal transduction mediated by tyrosine kinases, to use thereof in the treatment of illnesses, in particular tumor diseases and benign prostate hyperplasia (BPH), diseases of the lungs and respiratory tracts, and to production thereof.
L'invention concerne des hétérocycles substitués par cyclohexyloxy représentés par la formule générale (I), leurs stéréoisomères, leurs mélanges et leurs sels, en particulier leurs sels physiologiquement acceptables comprenant des acides inorganiques et organiques, qui présentent des propriétés pharmacologiques intéressantes, en particulier une action inhibitrice de la transduction du signal médiée par les tyrosine kinases, leur utilisation pour le traitement de maladies, en particulier de maladies tumorales, de même que de l'hyperplasie bénigne de la prostate (HBP), de maladies pulmonaires et respiratoires, ainsi que la préparation desdits composés.
Himmelsbach Frank
Jung Birgit
Lotz Ralf
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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