C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2733159
The present invention relates to cyclohexylol-substituted heterocyclics of the general formula (I), to tautomers thereof, to stereoisomers thereof, to mixtures thereof and to salts thereof, in particular physiologically compatible salts thereof containing inorganic or organic acids and bases and having valuable pharmacological properties, in particular an inhibiting effect on the signal transduction mediated by tyrosine kinases, to the use thereof in the treatment of illnesses, in particular tumor diseases and benign prostate hyperplasia (BPH), diseases of the lungs and respiratory tracts, and to the production thereof.
L'invention concerne des hétérocycles substitués par cyclohexyloxy représentés par la formule générale (I), leurs tautomères, leurs stéréoisomères, leurs mélanges et leurs sels, en particulier leurs sels physiologiquement acceptables comprenant des acides inorganiques et organiques, qui présentent des propriétés pharmacologiques intéressantes, en particulier une action inhibitrice de la transduction du signal médiée par les tyrosine kinases, leur utilisation pour le traitement de maladies, en particulier de maladies tumorales, de même que de l'hyperplasie bénigne de la prostate (HBP), de maladies pulmonaires et respiratoires, ainsi que la préparation desdits composés.
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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