C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/416 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2647677
The present invention discloses novel compounds of Formula (I): having 11.beta.-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I), as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11.beta.-HSD type 1 activity.
La présente invention concerne de nouveaux composés de formule I : (I) ayant une activité antagoniste de la 11.beta.-HSD de type 1, ainsi que des procédés servant à préparer de tels composés. Dans un autre mode de réalisation, l'invention concerne des compositions pharmaceutiques comprenant des composés de formule I, ainsi que des procédés d'utilisation des composés et des compositions pour traiter le diabète, l'hyperglycémie, l'obésité, l'hypertension, l'hyperlipidémie, un syndrome métabolique et d'autres affections associées à l'activité de la 11.beta.-HSD de type 1.
Aicher Thomas Daniel
Anzeveno Peter Biagio
Krasutsky Alexei Pavlovych
Li Renhua
Mabry Thomas Edward
Eli Lilly And Company
Gowling Lafleur Henderson Llp
LandOfFree
Cyclohexylpyrazole-lactam derivatives as inhibitors of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cyclohexylpyrazole-lactam derivatives as inhibitors of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclohexylpyrazole-lactam derivatives as inhibitors of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2089892