Cyclooxygenase and 5-lipoxygenase inhibiting n(3-biphenylyl-...

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 259/06 (2006.01) A61K 31/16 (2006.01) A61K 31/275 (2006.01) C07C 17/263 (2006.01) C07C 33/28 (2006.01) C07C 33/48 (2006.01) C07C 45/00 (2006.01) C07C 45/72 (2006.01) C07C 49/235 (2006.01) C07C 239/10 (2006.01) C07C 239/22 (2006.01) C07C 255/49 (2006.01) C07C 255/53 (2006.01) C07C 255/56 (2006.01) C07C 255/64 (2006.01) C07C 271/00 (2006.01) C07C 271/14 (2006.01) C07C 275/64 (2006.01) C07D 309/12 (2006.01)

Patent

CA 2161544

The present invention is concerned with novel hydroxamic acid derivatives of formula (I) and their use in medical therapy, particularly in the prophylaxis or treatment of clinical conditions for which an inhibitor of the lipoxygenase or cyclooxygenase mediated arachidonic acid metabolic pathway is indicated. The invention also relates to pharmaceutical formulations and processes for the preparation of compounds according to the invention. In formula (I), X is cyano, fluoro, or chloro; or a salt, solvate, or physiologically functional derivative thereof.

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