C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/60 (2006.01) A61K 47/42 (2006.01) C07K 7/62 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2096889
Abstract HOE 92/F 145 Cyclopeptides and their use as absorption promoter when applied to the mucosa The invention relates to a compound of the formula I (I) Image or a physiologically tolerated salt thereof, in which X is A basic L- or D-amino acid, Y is a neutral or basic L- or D-amino acid, Z is a neutral or basic L- or D-amino acid, which can be identical to or different from Y, R1 is an N-bonded acyl radical of the formula II (II) Image in which Ar is a phenyl radical, which is optionally substituted by 1, 2 or 3 identical or different radicals from the series comprising hydroxyl, (C1-C4-alkoxy, amino, carboxyl, (C1-C4)-alkylamino and halogen, or is a 2-aminothiazol-4-yl radical, p is an integer from zero to 4 and q, n, m and 1 indepen- dently of one another are zero or 1. The invention additionally relates to the use of compounds of the formula I and physiologically tolerated salts thereof for promoting the absorption of peptides and proteins when applied to the mucosa, and pharmaceutical formulations which contain a pharmacologically active amount of one or more peptides or proteins and a compound of the formula I or physiologically tolerated salts thereof.
Ditzinger Gunter
Durckheimer Walter
Merkle Hans-Peter
Sandow Jurgen
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
LandOfFree
Cyclopeptides and their use as absorption promoters when... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cyclopeptides and their use as absorption promoters when..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclopeptides and their use as absorption promoters when... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1668302