Cyclophilin-type peptidyl-prolyl cis/trans isomerase

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/61 (2006.01) A61K 38/43 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 9/90 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2340785

The invention provides a human cyclophilin-type peptidyl-prolyl cis/trans isomerase (CPCI) and polynucleotides which identify and encode CPCI. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of CPCI.

L'invention concerne une peptidyl-prolyle cis/trans isomérase du type cyclophiline, ainsi que des polynucléotides identifiant et codant cette isomérase; elle concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et antagonistes. L'invention concerne encore des méthodes de diagnostic, traitement ou prévention de troubles associés à l'expression de cette isomérase.

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