Cyclophosphamide - alanine lyophilizates

Details Cyclophosphamide - alanine lyophilizates Cyclophosphamide - alanine lyophilizates

A - Human Necessities

61

K

167/250

A61K 31/675 (2006.01) A61K 9/19 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2013474

A stable rapidly dissolving lyophilized composition of cyclophosphamide and alanine is provided which contains an amount of water which ranges from approximately 0 parts to about 10 parts per 100 parts of cyclophosphamide; the composition is preferably prepared from a solution containing at least 1.7% (W/V) weight of alanine and having a pH in the range of 5 to 7. The composition is particularly characterized by not requiring rehydration prior to storage.

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