Cyclopropane derivatives and anti-viral agent containing the...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/54 (2006.01) A61K 31/505 (2006.01) C07D 239/553 (2006.01)

Patent

CA 2134050

ABSTRACT Cyclopropane derivatives of the general formula (I): Image (I) wherein R1 and R2 are the same or different and each represent a hydrogen atom or an acyl group, R3 represents a halogen atom, an alkyl group having 2 to 5 carbon atoms, a trifluoromethyl group, a 2-haloalkyl group, a 1- alkenyl group, a 2-halo-1-alkenyl group or a 1-alkynyl group, and their pharmaceutically acceptable salts have an anti-viral activity and are especially effective against varicella-zoster viruses and herpes simplex viruses.

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