C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/00 (2006.01) A61K 31/52 (2006.01)
Patent
CA 2136159
ABSTRACT OF THE DISCLOSURE Cyclopropane derivatives of the general formula: Image (I) wherein R1 and R2 are the same or different and each represent a hydrogen atom or a group of formula: Image (II) wherein R3 represents an alkyl group containing 1 to 6 carbon atoms, with the proviso that at least one of R1 and R2 is a group of the formula (II), X represents a hydrogen or halogen atom, a hydroxyl group or an amino group, and Y represents a hydrogen atom, a hydroxyl group or an amino group, and their pharmaceutically acceptable salts have antiviral activity as well as improved water solubility and oral absorbability.
Ikemura Oasamu
Iwayama Satoshi
Ohmura Yuko
Okunishi Masahiko
Onishi Tomoyuki
Ajinomoto Co. Inc.
Ogilvy Renault
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