Cyclopropyl amine derivatives

Details Cyclopropyl amine derivatives Cyclopropyl amine derivatives

C - Chemistry, Metallurgy

07

D

C07D 295/14 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61P 25/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2709081

Compounds of formula (I) wherein R1, R2, R3, R3a, R3b, R4, and R5 are defined in the description, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).

Selon la présente invention, les composés de formule (I), où R1, R2, R3, R3a, R3b, R4 et R5 sont définis dans la description, sont utiles dans le cadre du traitement des pathologies ou des troubles inhibés ou améliorés par les ligands des récepteurs de l'histamine-3. la présente invention a également trait à des compositions pharmaceutiques comprenant les ligands des récepteurs de l'histamine-3, à des procédés d'utilisation de ces composés et compositions et à un processus de préparation des composés conformément à la portée de la formule (I).

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