Cyclopropyl derivative lipoxygenase inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 275/64 (2006.01) A61K 31/17 (2006.01) A61K 31/33 (2006.01) C07C 259/06 (2006.01) C07C 259/08 (2006.01) C07D 207/335 (2006.01) C07D 209/14 (2006.01) C07D 213/04 (2006.01) C07D 213/30 (2006.01) C07D 213/40 (2006.01) C07D 213/61 (2006.01) C07D 213/643 (2006.01) C07D 213/65 (2006.01) C07D 213/68 (2006.01) C07D 215/02 (2006.01) C07D 277/28 (2006.01) C07D 277/34 (2006.01) C07D 277/64 (2006.01) C07D 307/34 (2006.01) C07D 307/52 (2006.01) C07D 307/56 (2006.01) C07D 307/81 (2006.01) C07D 317/58 (2006.01) C07D 3

Patent

CA 2032251

Abstract Certain carbocyclic aryl- and heterocyclic aryl- substituted cyclopropyl N- hydroxyureas, N-hydroxy-carboxarnides, and N-acyl-N-hydroxyamines inhibit 5- and/or 12-lipoxygenase and are useful in the treatment of inflammatory disease states.

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