Cyclopropyl squalene derivatives and their use as inhibitors...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 43/188 (2006.01) A61K 31/075 (2006.01)

Patent

CA 2078871

The present invention relates to a group of compounds which are novel squalene derivatives containing the cyclopropyloxy functionality and which act to inhibit the=_ synthesis of cholesterol in mammals and in fungi. The compounds have the formula Image wherein Z is a radical selected from the group consisting of the radicals represented by the Formula A, B, C and D as below: Image

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