C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 255/42 (2006.01) A61K 31/275 (2006.01) A61K 31/36 (2006.01) C07C 255/43 (2006.01) C07D 317/64 (2006.01)
Patent
CA 2162916
Compounds of general formula (I), wherein R¿1?-R¿3? and R¿6?-R¿8? are, in particular, fluorine, chlorine, methyl, ethyl, isopropyl, tert-butyl, methoxyl and ethoxyl radicals, R¿4? is hydrogen or lower alkyl, and R¿5? is an optionally substituted phenyl or phenoxy radical; for use as calcium channel antagonists and serotonin 5-HT¿2? antagonists, and particularly as neuroprotective agents.
Les composés de l'invention répondent à la formule générale (I), dans laquelle: R1 à R3 et R6 à R8 représentent notamment des radicaux fluor, chlore, méthyle, éthyle, isopropyle, tert-butyle, méthoxyle et éthoxyle; R4 est un hydrogène ou un alkyle inférieur; R5 est un radical phényle ou phénoxy éventuellement substitué. Application comme antagonistes des canaux calcium et antagonistes de la sérotonine 5-HT2 en particulier comme neuroprotecteurs.
Corbera-Arjona Jordi
Frigola-Constansa Jordi
Laboratorios Del Dr. Esteve S.a.
Robic
LandOfFree
Cyclopropylacetonitrile derivatives, preparation thereof and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cyclopropylacetonitrile derivatives, preparation thereof and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclopropylacetonitrile derivatives, preparation thereof and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1852695