Cyclopropylmethylamine derivatives

Details Cyclopropylmethylamine derivatives Cyclopropylmethylamine derivatives

A - Human Necessities

61

K

260/602.1

A61K 31/135 (2006.01) A61K 31/13 (2006.01)

Patent

CA 1060049

NOVEL CYCLOPROPYLMETHYLAMINE DERIVATIVES Abstract of the Disclosure Novel cyclopropylmethylamine compounds of the formula: Image wherein Ar1 is a phenyl group substituted by at least one of halogen, C1-C4 alkyl, C1-C4 alkoxy and trifluoromethyl, of which at least one is present at the o- or m-position, Ar2 represents a phenyl group or such group substituted by at least one of halogen and C1-C4 alkyl, R represents hydrogen, C1-C4 alkyl or C2-C4 hydroxyalkyl and R' represents C1-C4 alkyl or C2-C4 hydroxyalkyl, are described. They are anti- depressants and anorexies and can be produced by reduction of compounds of the formula: Image or by condensation of compounds of the formula: Image with amines of the formula: Image

241210

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