Cyclosporin a derivatives modified at position 1 and...

Details Cyclosporin a derivatives modified at position 1 and... Cyclosporin a derivatives modified at position 1 and...

C - Chemistry, Metallurgy

07

K

530/7.64

C07K 7/64 (2006.01) A61K 38/13 (2006.01) A61P 37/06 (2006.01) G01N 21/64 (2006.01) G01N 33/53 (2006.01) G01N 33/533 (2006.01) G01N 33/542 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01) G01N 33/94 (2006.01)

Patent

CA 1341463

The present invention is directed to a fluorescence polarization immunoassay for cyclosporin A and metabolites thereof. The present invention also relates to novel cyclosporin A derivative compounds useful in fluorescence polarization techniques. Included among the novel compounds are cyclosporin A derivatives where the amino acid in the first position is altered. The cyclosporin A derivatives are useful in forming immunogens for raising antibodies specific to cyclosporin A and metabolites thereof.

562525

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