Cyclosporin-containing soft capsule preparations

Details Cyclosporin-containing soft capsule preparations Cyclosporin-containing soft capsule preparations

A - Human Necessities

61

K

A61K 38/13 (2006.01) A61K 9/48 (2006.01) A61K 47/14 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2240705

The present invention relates to a cyclosporin-containing soft capsule preparation which comprises a composition containing cyclosporin as an active ingredient; a hydrophilic component polyethylene glycol or a non-hydrophilic component propylene carbonate or their mixture, a mixture of an esterified compound of fatty acid and primary alcohol, medium chain fatty acid triglyceride and fatty acid monoglyceride as an oil component; and a surfactant having an HLB (Hydrophilic Lipophilic Balance) value of 8 to 17, in a gelatin shell containing polyethylene glycol and propylene glycol as a plasticizer.

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