Cyclosporin-containing sustained release pharmaceutical...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/52 (2006.01) A61K 9/00 (2006.01) A61K 38/13 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2472242

The present invention relates to a cyclosporin-containing sustained release pharmaceutical composition. More particularly, the present invention is directed to a cyclosporin-containing sustained release pharmaceutical composition essentially comprising a biodegradable polymer, cyclosporin and a release modifier encapsulated therein, in which cyclosporin and the release modifier are encapsulated in the biodegradable polymer and the release modifier is at least one member selected from the group consisting of hydrophilic release modifiers and lipophilic release modifiers.

La présente invention concerne une composition pharmaceutique à libération prolongée contenant de la cyclosporine. De manière plus spécifique, cette invention concerne une composition à libération prolongée contenant de la cyclosporine qui est principalement constituée d'un polymère biodégradable, de cyclosporine et d'un modificateur de libération encapsulé, la cyclosporine et le modificateur de libération étant encapsulés dans le polymère biodégradable et le modificateur de libération étant au moins un élément sélectionné dans le groupe formé par les modificateurs de libération hydrophiles et les modificateurs de libération lipophiles.

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