Cyclosporin derivatives

Details Cyclosporin derivatives Cyclosporin derivatives

C - Chemistry, Metallurgy

07

K

530/7.64, 167/10

C07K 7/64 (2006.01) A61K 38/13 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2021788

Hydroxy-substituted [(D)Ser]8-Ciclosporin derivatives, particularly [0-(2-hydroxyethyl)(D)Ser]8-Ciclosporin, have advantageous pharmacological properties and are useful as immunosuppressants, for example in the treatment of transplant rejection and autoimmune diseases.

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