Cyclosporin derivatives and derivative conjugates

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/64 (2006.01) G01N 33/532 (2006.01)

Patent

CA 2086267

TITLE Cyclosporin Derivatives and Derivative Conjugates ABSTRACT Cyclosporin compounds having a reactive residue attached to an intact cyclosporin ring, (and in particular compounds wherein the reactive residues are derivatives of a 2-N-methyl-(R)-((E)-2-butenyl)-4-methyl- L-threonine moiety on the intact cyclosporin ring), are used in the production of cyclosporin conjugates and conjugate complexes.

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