Cyclosporin emulsions

Details Cyclosporin emulsions Cyclosporin emulsions

A - Human Necessities

61

K

A61K 38/13 (2006.01) A61K 9/107 (2006.01) A61K 47/24 (2006.01)

Patent

CA 2250970

This invention comprises pharmaceutical compositions consisting essentially of an oil-in-water emulsion containing a synthetic medium chain triglyceride in which is dissolved a therapeutically effective amount of a cyclosporin, phospholipid and optionally free fatty acid or a salt thereof, non-ionic surfactant, ionic surfactant, glycerol, salts, buffers, preservative, osmotic modifier and antioxidant.

Compositions pharmaceutiques principalement constituées d'une émulsion du type huile-dans-eau qui contient un triglycéride de synthèse à chaîne moyenne dans lequel on a dissous une quantité thérapeutiquement efficace d'une cyclosporine, d'un phospholipide et facultativement d'un acide gras libre ou d'un sel de ce dernier, d'un tensio-actif non ionique, d'un tensio-actif ionique, de glycérol, de sels, de tampons, d'un conservateur, d'un modificateur osmotique et d'un antioxydant.

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