Cyclothiocarbamative derivatives as pr modulators and use...

A - Human Necessities – 61 – K

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A61K 31/535 (2006.01) A61K 8/49 (2006.01) A61K 31/536 (2006.01) A61K 31/56 (2006.01) A61K 31/565 (2006.01) A61Q 7/00 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2489815

The present invention provides for the use of a compound of formula (I) or formula (II) in treating skin disorders, wherein formula (I) is: and wherein R1-R5 and Q1 are defined as described herein. Specifically, methods for treating acne, hirsutism, and conditioning the skin are described. Also provided are novel PR modulators of formula (II) and uses thereof.

L'invention concerne l'utilisation d'un composé représenté par la formule (I) ou par la formule (II) permettant de traiter des troubles cutanés, la formule (I) possédant une structure telle que représentée, et R?1¿-R?5¿ et Q?1¿ étant tels que décrits dans les spécifications. L'invention concerne, plus particulièrement, des méthodes permettant de traiter l'acné et l'hirsutisme et de conditionner la peau. L'invention concerne également de nouveaux modulateurs PR représentés par la formule (II) et leurs utilisations.

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