Cyclylamine derivatives as calcium channel blockers

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 233/00 (2006.01) A61K 31/165 (2006.01) A61K 31/277 (2006.01) A61K 31/395 (2006.01) A61P 29/00 (2006.01) C07C 255/00 (2006.01) C07C 317/32 (2006.01) C07D 207/00 (2006.01) C07D 213/00 (2006.01) C07D 231/00 (2006.01) C07D 241/00 (2006.01) C07D 261/00 (2006.01) C07D 277/00 (2006.01) C07D 295/192 (2006.01) C07D 309/00 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2722704

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity are disclosed. Specifically, a series of compounds of substituted or unsubstituted cyclylamine derivatives as shown in formulas (1).

L'invention porte sur des procédés et des composés qui permettent d'améliorer les états caractérisés par une activité non désirée du canal calcique, en particulier une activité non désirée du canal calcique N et/ou T. L'invention concerne, en particulier, une série de composés de dérivés de cyclylamine substitués ou non substitués tels qu'illustrés dans les formules (1).

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