C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 4/00 (2006.01) A61K 51/08 (2006.01) C07K 5/00 (2006.01)
Patent
CA 2745946
The present invention relates to a peptide tag which can be used to bind a Technetium (Tc) or Rhenium (Re) radionuclide to a protein of interest which comprises the peptide tag and allows the imaging of such a tagged protein. In particular the present invention relates to a peptide tag which chelates a Tc or Re atom but which does not comprise a Cysteine residue.
La présente invention concerne une étiquette peptidique pouvant être utilisée pour lier un radionucléide technétium (Tc) ou rhénium (Re) et une protéine d'intérêt qui renferme ladite étiquette peptidique, ladite étiquette permettant l'imagerie d'une telle protéine marquée. L'invention concerne en particulier une étiquette peptidique chélatant un atome de Tc ou Re mais ne contenant aucun résidu de cystéine.
Cuniasse Philippe
Le Clainche Loic
Lecoq Alain
Masella Michel
Thai Robert
Commissariat A. L'energie Atomique Et Aux Energies Alternatives
Robic
LandOfFree
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