Cysteine/glycine rich peptides

Details Cysteine/glycine rich peptides Cysteine/glycine rich peptides

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) A23C 9/20 (2006.01) A23J 3/34 (2006.01) A23L 1/305 (2006.01) A23L 2/66 (2006.01) A61K 38/01 (2006.01) C07K 2/00 (2006.01)

Patent

CA 2359606

Described is a method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising cysteine containing proteins, comprising the steps of: a) cleaving the proteins of the protein source into peptides; b) digesting the peptides obtained in step a) by an exopeptidase, the action of which is at least attenuated at the position of a cysteine in the peptide, therewith forming digested peptides having a terminal cysteine; c) purifying the digested peptides, and the use of the preparation as active component in a medicament, especially for the treatment of conditions mediated by oxidative damage and for the elevation of cellular glutathion levels in the human or animal body.

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