Cysteine protease and serine protease inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 249/18 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07C 59/84 (2006.01) C07D 235/22 (2006.01) C07D 253/08 (2006.01) C07D 311/82 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2197306

The present invention is directed to irreversible inhibitors of serine and cysteine proteases which most preferably contain a 1-oxytriazole or 1- oxyimidazole functionality. Methods for the use of the protease inhibitors are also described.

On décrit des inhibiteurs irréversibles des sérine et cystéine protéases contenant, de préférence, une fonctionnalité 1-oxytriazole ou 1-oxyimidazole. On décrit également l'utilisation de ces inhibiteurs.

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