Cysteinyl protease inhibitors

Details Cysteinyl protease inhibitors Cysteinyl protease inhibitors

C - Chemistry, Metallurgy

07

K

C07K 5/08 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2376081

Amino acid di- and tri-peptide analogs having C-terminal vinylic groups, pharmaceutical compositions containing the analogs and methods of treating diseases using cysteinyl protease inhibitors; particularly neurodegenerative, autoimmune, cognitive disorders, stroke and traumatic injury.

L'invention concerne des analogues d'acides aminés di- et tripeptidiques comprenant des groupes vinyliques C-terminaux, des compositions pharmaceutiques contenant ces analogues ainsi que l'utilisation d'inhibiteurs de cystéine protéase pour le traitement de pathologies, en particulier de troubles neurodégénératifs, auto-immuns, cognitifs, d'accidents vasculaires cérébraux et de lésions traumatiques.

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