Cytarabine monophosphate prodrugs

Details Cytarabine monophosphate prodrugs Cytarabine monophosphate prodrugs

C - Chemistry, Metallurgy

07

H

C07H 19/10 (2006.01) A61K 31/7068 (2006.01) A61P 35/00 (2006.01) C07F 9/6574 (2006.01) C07H 19/04 (2006.01)

Patent

CA 2503730

A compound of Formula III: (see formula III) or a pharmaceutically acceptable salt thereof, its preparation and uses, e.g., in treatment of diseases of the liver, are described.

L'invention concerne des composés de formule I, leur préparation et leurs utilisations. Dans la formule I, M et V représentent des cis l'un par rapport à l'autre et MH représente une cytarabine ; l'oxygène 5' de ladite cytarabine est fixée au phosphore ; V représente du 4-pyridyl. L'invention concerne également des promédicaments et des sels pharmaceutiquement acceptables de ces composés.

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