Cytidine analogs for treatment of myelodysplastic syndromes

Details Cytidine analogs for treatment of myelodysplastic syndromes Cytidine analogs for treatment of myelodysplastic syndromes

A - Human Necessities

61

K

A61K 31/7068 (2006.01) A61P 35/02 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2742252

The present invention provides methods of treating a patient having a higher risk myelodysplastic syndrome, which comprises administering to a patient having a higher risk myelodysplastic syndrome a therapeutically effective amount of a cytidine analog. The cytidine analog includes 5 -aza-2'-deoxy cytidine, 5-azacytidine, 5-aza-2'-deoxy- 2',2'-difluorocytidine, 5-aza-2'-de- oxy-2'-fluorocytidine, 2'-deoxy-2',2'-difluorocytidine, cytosine 1-.beta.-D- arabinofuranoside, 2(1H) pyrimidine riboside, 2'-cyclocyti- dine, arabinofuanosyl-5-azacytidine, dihydro-5-azacytidine, N-octadecyl- cytarabine, and elaidic acid cytarabine

La présente invention concerne des procédés de traitement d'un patient présentant un plus grand risque de syndrome myélodysplasique, qui comprend l'administration à un patient présentant un plus grand risque de syndrome myélodysplasique d'une quantité thérapeutiquement efficace d'un analogue de la cytidine. L'analogue de la cytidine comprend la 5-aza-2'-désoxy cytidine, la 5-azacytidine, la 5-aza-2'-désoxy-2',2'-difluorocytidine, la 5-aza-2'-désoxy-2'-fluorocytidine, la 2'-désoxy-2',2'-difluorocytidine, le 1-ß-D-arabinofuranoside de cytosine, le riboside de la 2(1H) pyrimidine, la 2'-cyclocytidine, l'arabinofuanosyl-5-azacytidine, la dihydro-5-azacytidine, la N4-octadécyl-cytarabine, et l'acide élaïdique cytarabine.

Affiliated with

Also associated with

Rating

Cytidine analogs for treatment of myelodysplastic syndromes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cytidine analogs for treatment of myelodysplastic syndromes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cytidine analogs for treatment of myelodysplastic syndromes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1793948