Cytochrome c acetylation

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/48 (2006.01) A61K 45/00 (2006.01) C07K 14/80 (2006.01) C12N 9/80 (2006.01) C12Q 1/26 (2006.01) C12Q 1/34 (2006.01)

Patent

CA 2509607

Modulation of cytochrome c acetylation, e.g., with a SIR polypeptide, enables interventions that modulate lifespan regulation and cell proliferation, e.g., by modulating apoptosis and/or mitochondrial function such as respiration.

La modulation de l'acétylation du cytochrome c, par exemple avec un polypeptide SIR, permet des interventions qui modulent la régulation de la durée de vie et la prolifération cellulaire, notamment par modulation de l'apoptose et/ou de la fonction mitochondriale telle que la respiration.

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