Cytochrome p450 oxygenases and their uses

Details Cytochrome p450 oxygenases and their uses Cytochrome p450 oxygenases and their uses

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) A01K 67/027 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 15/63 (2006.01) C12N 15/82 (2006.01) C12P 17/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2390504

Oxygenase enzymes and the use of such enzymes to produce paclitaxel (Taxol TM), related taxoids, as well as interme- diates in the Taxol biosynthetic pathway are disclosed. Also disclosed are nucleic acid sequences encoding the oxygenase enzymes.

La présente invention concerne des enzymes oxygénases et leur utilisation pour produire du paclitaxel (Taxol<TM>), les taxoïdes associés, ainsi que des intermédiaires intervenant dans la voie de synthèse biologique du Taxol. Cette invention concerne également des séquences d'acide nucléique codant pour ces enzymes oxygénases.

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