C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 11/04 (2006.01) A61K 9/66 (2006.01) A61K 35/12 (2006.01) A61K 47/38 (2006.01) C12N 9/02 (2006.01) C12N 15/867 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2250173
A replication-defective retroviral vector carrying a cytochrome P450 gene under transcriptional control of target cell specific regulatory elements or promoters, or X-ray inducible promoters.
L'invention porte sur un vecteur rétroviral comportant une anomalie de réplication et porteur d'un gène du cytochrome P450 placé sous le contrôle transcriptionnel d'éléments régulateurs ou promoteurs spécifiques de la cellule cible, ou de promoteurs pouvant être induits par les rayons X.
Gunzberg Walter H.
Karle Peter
Saller Robert Michael
Bavarian Nordic A/s
Bavarian Nordic Research Institute
Gsf - Forschungszentrum Fur Umwelt Und Gesundheit Gmbh
Shapiro Cohen
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