Cytokine-expressing cellular vaccines for treatment of...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A01N 63/00 (2006.01) A61K 48/00 (2006.01) G01N 33/537 (2006.01)

Patent

CA 2577989

Genetically modified cytokine-expressing cells for use as vaccines in the treatment of prostate cancer are provided. More specifically, genetically modified, GM-CSF expressing cells as a means to generate an enhanced immune response to beta filamin and the use thereof in the treatment of prostate cancer are described.

L'invention concerne des cellules exprimant des cytokines génétiquement modifiées que l'on utilise comme vaccins dans le traitement du cancer de la prostate. Plus précisément, l'invention concerne des cellules exprimant du GM-CSF, génétiquement modifiées, comme moyen de produire une réponse immunitaire renforcée à la filamine bêta et leur utilisation dans le traitement du cancer de la prostate.

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