Cytokine-free growth and maintenance of progenitor cells

Details Cytokine-free growth and maintenance of progenitor cells Cytokine-free growth and maintenance of progenitor cells

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2485332

The invention pertains to methods and devices for the in vitro culture of hematopoietic progenitor cells in the absence of exogenously added hematopoietic growth factors. The hematopoietic progenitor cells are cultured in the absence of exogenously added hematopoietic growth factors without loss in cell progenitor cell numbers and/or functionality, while maintaining progenitor cell pluripotency.

L'invention concerne des procédés et des dispositifs de culture in vitro de cellules progénitrices hématopoïétiques en l'absence de facteurs de croissance hématopoïétiques exogènes ajoutés. Ces cellules sont cultivées en l'absence de facteurs de croissance hématopoïétiques exogènes ajoutés, sans perte au niveau du nombre de cellules progénitrices et/ou de la fonctionnalité, mais avec maintien de l'activité multipotente des cellules progénitrices.

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