Cytokine polypeptides

Details Cytokine polypeptides Cytokine polypeptides

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C12N 15/11 (2006.01) C12P 21/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2483698

This invention relates to TMEM7 and TMEM7-related cytokines and to new members of the human cytokine polypeptide family, to methods of making such polypeptides, to methods of using them to treat conditions and diseases involving proliferation and/or differentiation of cells from pluripotent stem cell precursors, and to methods of using them to identify compounds that alter cytokine polypeptide activities

La présente invention se rapporte à des cytokines TMEM7 et des cytokines liées à TMEM7, et à de nouveaux membres de la famille des polypeptides cytokines humains, à des procédés de fabrication desdits polypeptides, à des procédés d'utilisation de ces derniers dans le traitement d'états et de pathologies impliquant une prolifération et/ou une différenciation cellulaire à partir de cellules souches pluripotentes précurseurs, et à des procédés d'utilisation de ces derniers afin d'identifier des composés modifiant les activités des polypeptides cytokines.

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