Cytokine polypeptides

Details Cytokine polypeptides Cytokine polypeptides

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 45/00 (2006.01) C07K 1/14 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2446180

This invention relates to IMX129840 cytokines, including new mammalian cytokine polypeptides; to methods of making such polypeptides; to methods of using them to treat conditions and diseases involving proliferation and/or differentiation of cells from pluripotent stem cell precursors; and to methods of identifying compounds that alter IMX129840 cytokine polypeptide activities.

L'invention concerne des cytokines IMX129840 comportant de nouveaux polypeptides cytokines de mammifères, des procédés de fabrication de ces polypeptides, des procédés d'utilisation de ceux-ci en vue de traiter des conditions et des maladies impliquant la prolifération et/ou la différenciation de cellules de précurseurs de cellule ES totipotentes et des procédés d'identification de composants modifiant les activités des polypeptides cytokines IMX129840.

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